Related Patent Info
REPROGRAMMING METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS (IPSC)
| Inventor | ROUX, Pierre |
|---|---|
| Assignee | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
| Title of Invention | REPROGRAMMING METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS (IPSC) |
| Abstract | The present invention relates to a reprogramming method for producing iPSC by transducing somatic differentiated cells with a viral vector expressing Δ133p53β isoform, Δ133p53γ isoform or both of Δ133p53β and Δ133p53γ isoforms in the absence of induction of any Yamanaka transcription factors or without depleting or inducing mutations in p53 genes. |