Related Patent Info

METHODS AND COMPOSITIONS FOR INDUCING HEMATOPOIETIC CELL DIFFERENTIATION

Inventor VALAMEHR, Bahram, etc.
Assignee FATE THERAPEUTICS, INC.
Title of Invention METHODS AND COMPOSITIONS FOR INDUCING HEMATOPOIETIC CELL DIFFERENTIATION
Abstract

Provided is a method for differentiating pluripotent stem cells to hematopoietic lineage cells through hemogenic endothelium (HE) under feeder free conditions without EB formation, wherein the provided hematopoietic lineage cells comprise hematopoietic stem cells (HSC), hematopoietic multipotent progenitor cells (MPP), pre-T cell progenitor cells, pre-NK cell progenitor cells, T cell progenitor cells, NK cell progenitor cells, T cells, NK cells, NKT cells, or B cells.