Related Patent Info
MESENCHYMAL STEM CELLS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS
| Inventor | PROCKOP, Darwin, J., etc. |
|---|---|
| Assignee | THE TEXAS A&M UNIVERSITY SYSTEM, etc |
| Title of Invention | MESENCHYMAL STEM CELLS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS |
| Abstract | Provided is a method of producing mesenchymal stem cells from iPSCs comprising steps of; (1) iPSCs are cultured in the presence of a TGF-β inhibitor and in an atmosphere containing about 7 to 8 vol. % C02 for a period of time from about 20 day to about 35 days, (2) the cells obtained in (1) are transfered to a culture dish having a hydrophilic surface, and (3) the cells obtained in (2) are cultured in a medium containing a TGF-β inhibitor. |