Related Patent Info
METHODS FOR CONTROLLING CELL FATE AND CONSEQUENCES FOR DISEASE
| Inventor | HOCHEDLINGER, Konrad |
|---|---|
| Assignee | THE GENERAL HOSPITAL CORPORATION |
| Title of Invention | METHODS FOR CONTROLLING CELL FATE AND CONSEQUENCES FOR DISEASE |
| Abstract | Provided is a method for performing cellular reprogramming comprising steps of (a) contacting a somatic cell with an inhibitor of CAF-1 complex, Sumo2 or Nutd21, or combinations thereof, and (b) subjecting the somatic cell to a reprogramming protocol. Such inhibitors can improve both the speed and efficiency of cellular reprogramming. |