Related Patent Info
RESETTING PLURIPOTENT STEM CELLS
| Inventor | SMITH, Austin, etc. |
|---|---|
| Assignee | CAMBRIDGE ENTERPRISE LIMITED |
| Title of Invention | RESETTING PLURIPOTENT STEM CELLS |
| Abstract | Provided is a method of resetting a human stem cell to a more naive state, the method comprising: (1) culturing a human stem cell to be reset in a first medium comprising a MEK inhibitor and preferably a STAT3 activator, and (2) sustaining the cell in a second medium comprising a MEK inhibitor and a PKC inhibitor, and preferably a GSK3 inhibitor and a STAT3 activator. |