Patent Portfolio
COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASE
| Ref. No. | AJ201 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2019/025759（2019/6/21） |
| Pub. No. （Pub. date） |
WO2019/245060（2019/12/26） |
| Priority claim No. （Priority date） |
JP2018-119251（2018/06/22） |
| Patent No. | - |
| Inventor | INOUE, Haruhisa, etc. |
| Assignee | Kyoto University |
| Title of Invention | COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASE |
| Abstract | Present invention provides a therapeutic agent for hereditary spastic paraplegia (HSP) SPG4. More specifically, this invention pertains to a composition for preventing or treating a neurodegenerative disease such as HSP-SPG4 comprising a substance that inhibits the function of miR-33a as an active ingredient. The inventors completed this invention upon finding that inhibition of miR-33a function in the cortical neuron differentiated from HSP-SPG4 patient-derived iPS cells improved the axon length shortening of the neuron. |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2019-245060/3468100C7BCB371623CF365BF536B8B2713FA8D4C1EEFBDAE3211CF12B4BFD3F/50/en |
| Tag | Nerve (Neuron) |