Patent Portfolio

CARDIOMYOCYTE PROPAGATION PROMOTING AGENT AND USE THEREOF

Ref. No. AJ166
Appl. No.
(filing date)
PCT/JP2019/004631 (2019/2/8)
Pub. No.
(Pub. date)
WO2019/156216(2019/8/15)
Priority claim No.
(Priority date)

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Patent No.

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Inventor YOSHIDA, Yoshinori, etc.
Assignee Kyoto University
Title of Invention CARDIOMYOCYTE PROPAGATION PROMOTING AGENT AND USE THEREOF
Abstract

This invention relates to a compound (a retinoic acid receptor agonist, a PI3K inhibitor, or an IDH1 inhibitor) which activates cell cycle and thereby increases propagation efficiency of cardiomyocytes that may be derived from iPS cells, and a propagation method using the compound thereof. In a preferred embodiment, the compound is tamibarotene (AM80: retinoic acid receptor agonist).

Comments

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Updated date 2020/2/28
Information
(External link)
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2019-156216/B87E7D1D59F9E307FF7D2D1D16900D2151175E996D4B5915A6A9474FD4E6697F/50/en