Patent Portfolio

Novel method for inducing osteogenic differentiation

Ref. No. AJ193
Appl. No.
(filing date)
PCT/JP2018/046513(2018/12/18)
Pub. No.
(Pub. date)
WO2019/124348(2019/6/27)
Priority claim No.
(Priority date)

JP2017-243241 (2017/12/19)

Patent No.

-

Inventor TOGUCHIDA, Junya, etc.
Assignee Kyoto University
Title of Invention Novel method for inducing osteogenic differentiation
Abstract

The present invention provides a simple and one-step method for inducing osteogenic differentiation in a short period of time, comprising (1) a step of culturing pluripotent stem cells under feeder-free conditions, (2) a step of culturing in a mixed medium of an osteogenic differentiation induction medium and a pluripotent stem cell medium, including a ROCK inhibitor and a retinoic acid receptor α or β agonist, and (3) a step of culturing in an osteogenic differentiation induction medium including a retinoic acid receptor α or β agonist.

Comments

-

Updated date 2019/9/17
Information
(External link)
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2019-124348/9BBC41D36F33FA28AF4B7F26D390B9DBCF416E90DA0459630B8971D75B2195B8/50/en