Patent Portfolio

Prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis

Ref. No. AJ196
Appl. No.
(filing date)
PCT/JP2018/043242(2018/11/22)
Pub. No.
(Pub. date)
WO2019/103109(2019/5/31)
Priority claim No.
(Priority date)

JP2017-226368 (2017/11/24)

Patent No.

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Inventor INOUE, Haruhisa, etc.
Assignee Kyoto University
Title of Invention Prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis
Abstract

The present invention provides a prophylactic and/or therapeutic agent for ALS that comprises an Src/c-Abl pathway inhibitor. The present inventors found that the Src/c-Abl kinase pathway is a potential therapeutic target of ALS through screening of a chemical library of known compounds on an assay with motor neurons differentiated from SOD1-related ALS patient-derived iPS cells.

Comments

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Updated date 2019/7/19
Information
(External link)
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2019-103109/6482C9C29FE17DFC9AB559365ABF9FD600760DC0925BC3EFEEC469A6CA5C4526/50/en