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Method for producing neural crest cells and sympathetic neurons

Ref. No. AJ183
Appl. No.
(filing date)
PCT/JP2018/016758(2018/4/25)
Pub. No.
(Pub. date)
WO2018/199142(2018/11/1)
Priority claim No.
(Priority date)

JP2017-088926 (2017/04/27)

Patent No.

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Inventor NAKAHATA, Tatsutoshi, etc.
Assignee Kyoto University
Title of Invention Method for producing neural crest cells and sympathetic neurons
Abstract

Provided are a method for producing neural crest cells from pluripotent stem cells comprizing a step of culturing in a medium containing FGF2, retinoic acid and BMP4, a method for producing sympathetic neuron precursors from the neural crest cells comprizing a step of culturing in a medium containing a cytokine and BMP4, and a method for producing sympathetic neurons from the sympathetic neuron precursors comprizing a step of culturing in a medium containing a neurotrophic factor.

Comments

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Updated date 2019/6/13
Information
(External link)
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2018-199142/C8D5DD19EB2D5D65513E11A122206D44B04D3CAB2E08E42A8E22CC85BB8E2C39/50/en
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