Patent Portfolio

Method for producing steroidogenic cells

Ref. No. AJ182
Appl. No.
(filing date)
PCT/JP2018/003946(2018/2/6)
Pub. No.
(Pub. date)
WO2018/147257(2018/8/16)
Priority claim No.
(Priority date)

JP2017-020519 (2017/02/07)

Patent No.

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Inventor OSAFUNE, Kenji, etc.
Assignee Kyoto University
Title of Invention Method for producing steroidogenic cells
Abstract

Present invention provides a method for producing steroidogenic cells comprising a step of treating intermediate mesoderm cells (incl. those induced from pluripotent stem cells) with a dopamine D1 receptor agonist to induce differentiation into steroidogenic cells. Further provided is a method for screening a substance that induces differentiation into steroidogenic cells from intermediate mesoderm cells using the expression level of 3β-hydroxysteroid dehydrogenase as an indicator.

Comments

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Updated date 2019/6/13
Information
(External link)
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2018-147257/F7B110906BD249B3C0E5DCBE5D639C01B89DBB4E5D3596EB95AFAFD8983B2417/50/en