Patent Portfolio
Method for screening therapeutic and/or prophylactic agents for alzheimer's disease
| Ref. No. | AJ101 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2013/054199（2013/2/20） |
| Pub. No. （Pub. date） |
WO2013/140927（2013/9/26） |
| Priority claim No. （Priority date） |
JP2012-64094 (2012/3/21） |
| Patent No. | JP6335117 |
| Inventor | INOUE Haruhisa, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for screening therapeutic and/or prophylactic agents for alzheimer's disease |
| Abstract | Provided is a method for screening therapeutic or prophylactic agents for Alzheimer's disease comprising steps of: (1) contacting neurons or astrocytes differentiated from iPS cells of the disease patients with or without APP E693 mutation with a compound, and (2) measuring the amount of Aβoligomer, ER stress (BiP), cleaved caspase 4 activities, Transgelin, or oxidative stress (PRDX4 or ROS) in the neurons or astrocytes. |
| Comments |
- |
| Updated date | 2019/7/12 |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2013-140927/257D48CEC1FDBD6CE321A197C84B00EBAA78A6CB12CE489F2CA564C89CF439FF/50/en |
| Tag | Nerve (Neuron) |