Patent Portfolio
Induced pluripotent stem cell selection method and method for inducing differentiation to blood cells
| Ref. No. | AJ085 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2014/065497（2014/6/11） |
| Pub. No. （Pub. date） |
WO2014/200030（2014/12/18） |
| Priority claim No. （Priority date） |
JP2013-123485 (2013/6/12) |
| Patent No. | JP6493811 |
| Inventor | YAMANAKA Shinya, etc. |
| Assignee | Kyoto University |
| Title of Invention | Induced pluripotent stem cell selection method and method for inducing differentiation to blood cells |
| Abstract | Provided is a method for selecting iPS cells of a high capability to differentiate into blood cells on the basis of expression levels of one or more genes selected from a group consisting of TRIM58, CTSF, FAM19A5, and TCERGIL genes, or DNA methylation statuses of TRIM58, CSMD1 and/or FAM19A5 genes. Also provided is a method for producing hematopoietic stem cells and/or hematopoietic precursor cells by culturing the iPS cell in the presence of IGF2. |
| Comments |
- |
| Updated date | 2019/7/12 |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2014-200030/CFCA33F38CF49CA233FE59914E50253AEC0436D3C719F092CE4D1348066AEA5D/50/en |