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Preventative or therapeutic agent for tauopathy

Ref. No. AJ245
Appl. No. (filing date) PCT/JP2020/039450 (2020/10/20)
Pub. No. (Pub. date) WO2021/79887 (2021/04/29)
Priority claim No. (Priority date)

JP2019-194758(2019/10/25)

Patent No.

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Inventor INOUE Haruhisa, etc.
Assignee KYOTO UNIVERSITY, etc.
Title of Invention Preventative or therapeutic agent for tauopathy
Abstract

Provided is a prophylactic or therapeutic agent for tauopathy, that contains an α2δ inhibitor for voltage-gated calcium channels. The present invention has been completed based on the findings obtained from a screening assay using a cerebral cortical nerve cell produced from a familial FTLD-patient-derived iPS cell, which is an excellent tauopathy cell model exhibiting a cell death induced from the spontaneous tau oligomerization, coupled with a drug repositioning approach.

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