Patent Portfolio
Control system of protein translation
| Ref. No. | AJ239 |
|---|---|
| Appl. No. （filing date） |
JP2020-015891（2020/1/31） |
| Pub. No. （Pub. date） |
JP2021-122189（2021/8/30） |
| Priority claim No. （Priority date） |
- |
| Patent No. | - |
| Inventor | SAITO Hirohide, etc. |
| Assignee | Kyoto University |
| Title of Invention | Control system of protein translation |
| Abstract | Provided is a simplified protein translation control system, comprising: (1) a complex in which a translation activator and an RNA binding protein are bound, or an RNA encording the complex; and (2) an RNA not having a 7-methylguanosine 5'-phosphate structure and comprising 1 or more binding motifs for said RNA binding protein and a sequence encoding a protein. Since in the system of the invention it is possible to simultaneously achieve translation activation and suppression of a protein of interest, cell type-specific cell sorting, apoptosis induction, or genome editing can be performed safely. Further, the translation control of a protein can be limited to a particular timing or period of time, and thus a more complex protein translation control is enabled. |
| Comments |
- |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/JP-2020-015891/4634648C729018165100AA7BC28FE5F517FC9889A9B77F219A2739C20E0A8E6F/10/en |