Patent Portfolio
Mature-cardiomyocyte production method
| Ref. No. | AJ233 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2021/007466（2021/2/26） |
| Pub. No. （Pub. date） |
WO2021/172542（2021/9/2） |
| Priority claim No. （Priority date） |
JP2020-032716(2020/02/28) |
| Patent No. | - |
| Inventor | YOSHIDA Yoshinori, etc. |
| Assignee | Kyoto University |
| Title of Invention | Mature-cardiomyocyte production method |
| Abstract | Provided is a method for efficiently obtaining mature cardiomyocytes usable for drug screening and transplantation therapy from immature cardiomyocytes in a short period of time, the method comprising a step of increasing the expression level of cyclin-dependent kinase inhibitor 1 in immature cardiomyocytes. According to the invention, especially when combined with the differentiation from pluripotent stem cells, mature cardiomyocytes can be produced easily and in large quantities. |
| Comments |
- |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2021-172542/2FDB4B5D5E1BC07199A948B1D31CB943FD1F97C6CACF4056F788738EF01E19EF/50/en |