Mature-cardiomyocyte production method
| Ref. No. | AJ233 |
|---|---|
| Appl. No. (filing date) | PCT/JP2021/007466 (2021/02/26) |
| Pub. No. (Pub. date) | WO2021/172542 (2021/09/02) |
| Priority claim No. (Priority date) | JP2020-032716(2020/02/28) |
| Patent No. | - |
| Inventor | YOSHIDA Yoshinori, etc. |
| Assignee | Kyoto University |
| Title of Invention | Mature-cardiomyocyte production method |
| Abstract | Provided is a method for efficiently obtaining mature cardiomyocytes usable for drug screening and transplantation therapy from immature cardiomyocytes in a short period of time, the method comprising a step of increasing the expression level of cyclin-dependent kinase inhibitor 1 in immature cardiomyocytes. According to the invention, especially when combined with the differentiation from pluripotent stem cells, mature cardiomyocytes can be produced easily and in large quantities. |
| Comments | - |
| Publication |
