Method for inducing trophectoderm from naive pluripotent stem cells
|Appl. No. (filing date)||PCT/JP2020/43328 (2020/11/20)|
|Pub. No. (Pub. date)||WO2021/106765 (2021/06/03)|
|Priority claim No. (Priority date)||
|Inventor||TAKASHIMA Yasuhiro, etc.|
|Title of Invention||Method for inducing trophectoderm from naive pluripotent stem cells|
Provided is a method for inducing trophectoderm, which has been difficult to induce from conventional primed pluripotent stem cells, from naive pluripotent stem cells, comprising: culturing naive pluripotent stem cells in a medium containing two or more kinds selected from a TGFβ inhibitor, an MEK inhibitor, BMP, and a JAK inhibitor to induce differentiation into trophectoderm.