Patent Portfolio
Method for producing mature myotube cells from skeletal muscle stem cells
| Ref. No. | AJ214 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2020/027658（2020/7/16） |
| Pub. No. （Pub. date） |
WO2021/15086（2021/1/28） |
| Priority claim No. （Priority date） |
JP2019-134123(2019/07/19) |
| Patent No. | - |
| Inventor | SAKURAI Hidetoshi, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for producing mature myotube cells from skeletal muscle stem cells |
| Abstract | Provided is a method for producing mature myotube cells from skeletal muscle stem cells, comprising the steps of: (1) seeding skeletal muscle stem cells in a cell culture container and culturing the cells using a growth medium; (2) exchanging the medium with a differentiation medium and continuing the culture until some of the cells show a spindle shape; and (3) overlaying a gel, which contains an extracellular matrix component, on the cells and performing the culture using the differentiation medium. The mature myotube cells produced according to the invention from a patient with a genetic muscle disease can suitably be used for the pathological study of the disease and for drug screening. |
| Comments |
- |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2021-015086/50E8BA3726B4698BAB8EE285AF03972B47887AC93EAF0BE297DD04C7171AF039/50/en |
| Tag | Skeletal muscle |