Patent Portfolio
Method for producing nephron progenitor cells
| Ref. No. | AJ212 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2020/016969（2020/4/17） |
| Pub. No. （Pub. date） |
WO2020/213734（2020/10/22） |
| Priority claim No. （Priority date） |
JP2019-080272 (2019/04/19) |
| Patent No. | - |
| Inventor | OSAFUNE Kenji, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for producing nephron progenitor cells |
| Abstract | This invention relates to an efficient and stable method for producing nephron precursors or nephron organoids through a stepwise differentiation of pluripotent stem cells. More specifically, the invention is characterized by including the following two novel methods: (1) a method for producing late presomitic mesoderm cells, comprising a step of culturing presomitic mesoderm cells in a medium containing a specified set of growth factors and small molecule inhibitors; and (2) a method for producing posterior intermediate mesoderm cells, comprising a step of culturing late presomitic mesoderm cells in a medium containing a specified set of growth factors. |
| Comments |
- |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2020-213734/3DC542CB39D091C5BE7543491CE68572654AFCB355B7BA1BE413E37F22A3A7DA/50/en |