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Prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis

Ref. No. AJ196
Appl. No. (filing date) PCT/JP2018/043242 (2018/11/22)
Pub. No. (Pub. date) WO2019/103109 (2019/05/31)
Priority claim No. (Priority date)

JP2017-226368 (2017/11/24)

Patent No.

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Inventor INOUE, Haruhisa, etc.
Assignee Kyoto University
Title of Invention Prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis
Abstract

The present invention provides a prophylactic and/or therapeutic agent for ALS that comprises an Src/c-Abl pathway inhibitor. The present inventors found that the Src/c-Abl kinase pathway is a potential therapeutic target of ALS through screening of a chemical library of known compounds on an assay with motor neurons differentiated from SOD1-related ALS patient-derived iPS cells.

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Updated date 2019/07/19
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