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Method for inducing primitive endoderm from naive pluripotent stem cells

Ref. No. AJ194
Appl. No. (filing date) PCT/JP2018/041243 (2018/11/06)
Pub. No. (Pub. date) WO2019/093340 (2019/05/16)
Priority claim No. (Priority date)

JP2017-215115 (2017/11/07)

Patent No.

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Inventor TAKASHIMA, Yasuhiro, etc.
Assignee Kyoto University
Title of Invention Method for inducing primitive endoderm from naive pluripotent stem cells
Abstract

Provided is Provided is a method for preparing primitive endoderm from naive pluripotent stem cells in vitro, comprising a step in which the naive pluripotent stem cells are cultured in a culture medium containing BMP and FGF4, and preferably further containing at least one substance selected from PDGF, IL-6, TGFβ inhibitor, Wnt signal inhibitor, and retinoic acid.

Comments

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Updated date 2019/07/19
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