Patent Portfolio

Method for evaluating cell hyperstimulation toxicity

Ref. No. AJ191
Appl. No.
(filing date)
Pub. No.
(Pub. date)
Priority claim No.
(Priority date)

JP2017-230610 (2017/11/30)

Patent No.


Inventor INOUE, Haruhisa, etc.
Assignee Kyoto University
Title of Invention Method for evaluating cell hyperstimulation toxicity

Provided is a method for evaluating hyperstimulation toxicity of a test substance to a human neurocyte, comprising (1) a step of bringing a test substance into contact with a human neurocyte differentiated from a pluripotent stem cell, (2) a step of stimulating the human neurocyte, (3) a step of measuring the degree of hyperstimulation of the human neurocyte, and (4) a step of evaluating that the test substance has hyperstimulation toxicity to a human neurocyte when the hyperstimulation of the human neurocyte is enhanced in the presence of the test substance.



Updated date 2019/7/19
(External link)