Patent Portfolio
Method for evaluating cell hyperstimulation toxicity
| Ref. No. | AJ191 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2018/043917（2018/11/29） |
| Pub. No. （Pub. date） |
WO2019/107481（2019/6/6） |
| Priority claim No. （Priority date） |
JP2017-230610 (2017/11/30) |
| Patent No. | - |
| Inventor | INOUE, Haruhisa, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for evaluating cell hyperstimulation toxicity |
| Abstract | Provided is a method for evaluating hyperstimulation toxicity of a test substance to a human neurocyte, comprising (1) a step of bringing a test substance into contact with a human neurocyte differentiated from a pluripotent stem cell, (2) a step of stimulating the human neurocyte, (3) a step of measuring the degree of hyperstimulation of the human neurocyte, and (4) a step of evaluating that the test substance has hyperstimulation toxicity to a human neurocyte when the hyperstimulation of the human neurocyte is enhanced in the presence of the test substance. |
| Comments |
- |
| Updated date | 2019/7/19 |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2019-107481/8F2F11ACF919FEFDF63802EAB92C3884EC13E9ACEF8DFA15036ABBA33F82B398/50/en |
| Tag | Nerve (Neuron) |