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Method for obtaining artificial neuromuscular junction from pluripotent stem cells

Ref. No. AJ164
Appl. No.
(filing date)
PCT/JP2018/038690(2018/10/17)
Pub. No.
(Pub. date)
WO2019/078263(2019/4/25)
Priority claim No.
(Priority date)

JP2017-201364 (2017/10/17)

Patent No.

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Inventor SAITO Megumu, etc.
Assignee Kyoto University
Title of Invention Method for obtaining artificial neuromuscular junction from pluripotent stem cells
Abstract

This invention provides a method for producing an artificial neuromuscular junction, comprising: (i) a step for transiently expressing MyoD in pluripotent stem cells to induce myogenic differentiation; and (ii) a step for culturing the cells obtained in (i) in a medium containing a neurotrophic factor to induce neuronal differentiation.

Comments

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Updated date 2019/7/19
Information
(External link)
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2019-078263/364A861DDE25EDF3D780D4E2818F857D464B1F91018B6D5B7C56FEBEA5472EB0/50/en
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