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Method for obtaining artificial neuromuscular junction from pluripotent stem cells

Ref. No. AJ164
Appl. No. (filing date) PCT/JP2018/038690 (2018/10/17)
Pub. No. (Pub. date) WO2019/078263 (2019/04/25)
Priority claim No. (Priority date)

JP2017-201364 (2017/10/17)

Patent No.

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Inventor SAITO Megumu, etc.
Assignee Kyoto University
Title of Invention Method for obtaining artificial neuromuscular junction from pluripotent stem cells
Abstract

This invention provides a method for producing an artificial neuromuscular junction, comprising: (i) a step for transiently expressing MyoD in pluripotent stem cells to induce myogenic differentiation; and (ii) a step for culturing the cells obtained in (i) in a medium containing a neurotrophic factor to induce neuronal differentiation.

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Updated date 2019/07/19
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