Method for obtaining artificial neuromuscular junction from pluripotent stem cells
|Appl. No. (filing date)||PCT/JP2018/038690 (2018/10/17)|
|Pub. No. (Pub. date)||WO2019/078263 (2019/04/25)|
|Priority claim No. (Priority date)||
|Inventor||SAITO Megumu, etc.|
|Title of Invention||Method for obtaining artificial neuromuscular junction from pluripotent stem cells|
This invention provides a method for producing an artificial neuromuscular junction, comprising: (i) a step for transiently expressing MyoD in pluripotent stem cells to induce myogenic differentiation; and (ii) a step for culturing the cells obtained in (i) in a medium containing a neurotrophic factor to induce neuronal differentiation.