Patent Portfolio
Method for improving induced pluripotent stem cell generation efficiency
| Ref. No. | AJ033 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2011/051685（2011/1/21） |
| Pub. No. （Pub. date） |
WO2011/090221（2011/7/28） |
| Priority claim No. （Priority date） |
US 61/282,320 (2010/1/22) |
| Patent No. | JP5827220 |
| Inventor | YAMANAKA Shinya, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for improving induced pluripotent stem cell generation efficiency |
| Abstract | A method for improving iPS cell generation efficiency and a method for preparing iPS cells as well, comprising a step of introducing to a somatic cell a Myc variant having the following features: (1) having an activity to improve iPS cell generation efficiency comparable to, or greater than that of c-Myc; and (2) having a transformation activity lower than that of c-Myc ; or a nucleic acid encoding the same, together with a set of nuclear reprogramming factors, in a nuclear reprogramming step. |
| Comments |
- |
| Updated date | 2016/11/7 |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2011-090221/11C1BB14A2C1240ECEBFCB293EE5BE77E41B801E3CC4913881823C66E48426D5/50/en |