Related Patent Info

NEURAL CREST CELLS TO REVITALIZE CRANIAL ALLOGRAFTS

Inventor SHEYN, Dmitriy, etc.
Assignee CEDARS-SINAI MEDICAL CENTER
Title of Invention NEURAL CREST CELLS TO REVITALIZE CRANIAL ALLOGRAFTS
Abstract

Described herein are methods and compositions related to use of cranium-specific iPSC-derived cells that are demonstrated as capable of revitalizing structural allografts. Specifically, coating cranial allografts with mesenchymal stem cells derived from iPSC-derived neural crest cells provides an effective therapeutic avenue for cranial defects.