Related Patent Info
METHODS AND COMPOSITIONS FOR THE PRODUCTION OF OLIGODENDROCYTE PROGENITOR CELLS
| Inventor | KHOSHAKHLAGH, Parastoo, etc. |
|---|---|
| Assignee | PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
| Title of Invention | METHODS AND COMPOSITIONS FOR THE PRODUCTION OF OLIGODENDROCYTE PROGENITOR CELLS |
| Abstract | Provided is a method for producing oligodendrocyte progenitor cells (OPCs) comprising (i) a step of introducing into pluripotent stem cells at least four transcription factors selected from (a) OLIG2, (b) SOX9, (c) NKX6.1, (d) NKX6.2 and (e) OCT4, and (ii) a step of culturing the pluripotent stem cells to produce a population of cells comprising OPCs. |