Related Patent Info
METHOD FOR PRODUCING NEURAL CREST CELLS AND SYMPATHETIC NEURONS
| Inventor | NAKAHATA, Tatsutoshi, etc. |
|---|---|
| Assignee | KYOTO UNIVERSITY |
| Title of Invention | METHOD FOR PRODUCING NEURAL CREST CELLS AND SYMPATHETIC NEURONS |
| Abstract | Provided are a method for producing neural crest cells from pluripotent stem cells (e.g. iPS cells) comprising a step of culturing in a medium containing FGF2, retinoic acid and BMP4, and a method for producing sympathetic neurons from the neural crest cells comprising steps of culturing in a medium containing a cytokine and BMP4 to produce sympathetic neuron precursors, and then culturing in a medium containing a neurotrophic factor to thereby produce sympathetic neurons. |