Related Patent Info

METHOD FOR PRODUCING OSTEOBLAST CLUSTER USING HUMAN iPS CELLS

Inventor EGUSA, Hiroshi, etc.
Assignee TOHOKU UNIVERSITY
Title of Invention METHOD FOR PRODUCING OSTEOBLAST CLUSTER USING HUMAN iPS CELLS
Abstract

Provided is a method for producing an osteoblast cluster from human iPS cells (hiPSCs), comprising steps of (1) inducing formation of embryoid bodies (EBs) by a non-adhesive culture of hiPSCs, (2) inducing differentiation into mesodermal cells by a non-adhesive culture of EBs obtained in (1), and (3) inducing differentiation into osteoblasts by a non-adhesive culture of the mesodermal cells obtained in (2).