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ENDODERMAL CELL MASS, AND METHOD FOR PRODUCING ANY ONE OF THREE PRIMARY GERM LAYER CELL MASS FROM PLURIPOTENT CELLS

Inventor IBUKI Masato, etc.
Assignee KANEKA CORPORATION, etc.
Title of Invention ENDODERMAL CELL MASS, AND METHOD FOR PRODUCING ANY ONE OF THREE PRIMARY GERM LAYER CELL MASS FROM PLURIPOTENT CELLS
Abstract

The present invention provides a pluripotent stem cell-derived endodermal cell mass in which the content of undifferentiated cells is reduced and which contains endodermal cells capable of producing somatic cells that are suitable for a cell therapy preparation. The endodermal cell mass according to this invention is characterized by the relative expression levels of certain genes to that of OAZ1 (ornithine decarboxylase antizyme 1) gene.