Related Patent Info

PRODUCTION AND USE OF MOTOR NEURON DERIVED FROM PLURIPOTENT STEM CELL

Inventor INOUE, Haruhisa, etc.
Assignee KYOTO UNIVERSITY, etc.
Title of Invention PRODUCTION AND USE OF MOTOR NEURON DERIVED FROM PLURIPOTENT STEM CELL
Abstract

The present invention provides a method for producing a motor neuron from a pluripotent stem cell, comprising steps of (1) introducing a single Sendai virus vector carrying a nucleic acid encoding Lhx3, a nucleic acid encoding Ngn2 and a nucleic acid encoding Isl1 into a pluripotent stem cell, and (2) culturing the pluripotent stem cell for 2 days or longer.