Related Patent Info

COMPOSITIONS AND METHODS FOR ORGANOID GENERATION AND DISEASE MODELING

Inventor EVANS, Ronald, etc.
Assignee SALK INSTITUTE FOR BIOLOGICAL STUDIES
Title of Invention COMPOSITIONS AND METHODS FOR ORGANOID GENERATION AND DISEASE MODELING
Abstract

Provided is a method for generating a pancreatic islet organoid comprising a step of culturing an iPSC-derived beta-like cell in a 3D matrix comprising gellan gum, thereby generating a pancreatic islet organoid. The method may further comprise a step of culturing the iPSC-derived beta-like cell with an adipose-derived stem cell and/or an endothelial cell.