Related Patent Info
ENGINEERED ANUCLEATE CELLULAR AND EXTRACELLULAR VESICLES AS A NOVEL BIOLOGICS DELIVERY PLATFORM
| Inventor | CHENG, Linzhao, etc. |
|---|---|
| Assignee | THE JOHNS HOPKINS UNIVERSITY |
| Title of Invention | ENGINEERED ANUCLEATE CELLULAR AND EXTRACELLULAR VESICLES AS A NOVEL BIOLOGICS DELIVERY PLATFORM |
| Abstract | Provided is an induced pluripotent stem cell derived from a blood mononuclear cell that expresses a therapeutic entity, such as antibodies and nucleic acids, under the control of a HBB (hemoglobin beta) gene locus. The said induced pluripotent stem cell may form an anucleated erythrocyte comprising the therapeutic entity. |